Primary gastric lymphoma - The experience of a General Hospital
1985

Primary Gastric Lymphoma: A Study of 29 Cases

Sample size: 29 publication Evidence: moderate

Author Information

Author(s): T. Economopoulos, C. Alexopoulos, N. Stathakis, S. Styloyannis, J. Dervenoulas, S. Tsousis, S. Raptis

Primary Institution: University of Athens, Evangelismos Hospital

Hypothesis

What is the effectiveness of surgery combined with chemotherapy in treating primary gastric lymphoma?

Conclusion

The study suggests that combining curative surgery with chemotherapy yields promising results for patients with limited primary gastric lymphoma.

Supporting Evidence

  • 62% of patients achieved complete remission after 6 courses of chemotherapy.
  • 84% of complete responders are predicted to be alive at 4 years.
  • Advanced stage and tumor size greater than 10 cm adversely influenced survival.

Takeaway

Doctors looked at 29 people with a type of stomach cancer and found that surgery plus medicine worked well for many of them.

Methodology

The study analyzed 29 consecutive cases of primary gastric lymphoma treated with surgery and chemotherapy, assessing outcomes and survival rates.

Potential Biases

The assignment of chemotherapy regimens was not random, potentially introducing bias in treatment outcomes.

Limitations

The study is retrospective and includes a small number of patients, which may limit the generalizability of the findings.

Participant Demographics

The study included 20 men and 9 women with a median age of 55 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

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