Leisure time physical exercise during pregnancy and the risk of miscarriage: a study within the Danish National Birth Cohort
2007

Exercise During Pregnancy and Miscarriage Risk

Sample size: 92671 publication 10 minutes Evidence: moderate

Author Information

Author(s): Madsen M, Jørgensen T, Jensen ML, Juhl M, Olsen J, Andersen PK, Nybo Andersen A-M

Primary Institution: National Institute of Public Health Copenhagen K, Denmark

Hypothesis

Is there an association between leisure time physical exercise during pregnancy and the risk of miscarriage?

Conclusion

Exercise early in pregnancy is associated with an increased risk of miscarriage.

Supporting Evidence

  • High-impact exercise was associated with an increased risk of miscarriage.
  • Women who exercised more than 7 hours per week had a hazard ratio of 3.7 for miscarriage compared to nonexercisers.
  • No association was found between exercise and miscarriage risk after 18 weeks of gestation.
  • Approximately 47% of women reported exercising during pregnancy.

Takeaway

If pregnant women exercise a lot, especially with high-impact activities, it might increase the chance of losing the baby early on.

Methodology

The study used prospective data collection through interviews and analyzed the risk of miscarriage using Cox regression models.

Potential Biases

Recall bias may have affected how women reported their exercise habits after experiencing a miscarriage.

Limitations

Potential recall bias due to retrospective data collection and selection bias from case interviews.

Participant Demographics

The study included 92,671 pregnant women from Denmark, with a participation rate of about 35% of all pregnancies during the study period.

Statistical Information

P-Value

3.7

Confidence Interval

95% CI 2.9–4.7

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1111/j.1471-0528.2007.01496.x

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