Influences on Neurological and Neuropsychiatric Symptoms of Post-Acute COVID-19 Syndrome
Author Information
Author(s): Malioukis Alex, Snead R Sterling, Marczika Julia, Ambalavanan Radha
Primary Institution: Self Research Institute, Broken Arrow, OK, USA
Hypothesis
How do psychosocial and neuropsychological symptoms overlap with neurological ones in post-acute COVID-19 syndrome?
Conclusion
Psychological and psychosocial factors may interact with neurological symptoms, potentially increasing the persistence and severity of post-acute COVID-19 syndrome symptoms.
Supporting Evidence
- Up to 58% of PACS patients experience long-lasting fatigue.
- Anxiety and depression are common, affecting up to 29.6% and 35% of individuals, respectively.
- Up to 65% of COVID-19 survivors show cognitive impairment.
- Sleep disturbances affect up to 30% of PACS patients.
- Up to 51% of patients report symptoms similar to myalgic encephalitis/chronic fatigue syndrome.
Takeaway
People recovering from COVID-19 can feel tired and confused for a long time, and their feelings of sadness or worry can make these problems worse.
Methodology
A systematic review of literature from 2020 to 2024 examining the multifactorial causes of post-acute COVID-19 syndrome.
Potential Biases
Potential biases in study selection and reporting due to the evolving understanding of PACS.
Limitations
Variability and conflicting results across studies regarding PACS causes and interventions; reliance on cross-sectional data.
Participant Demographics
The syndrome can affect individuals across all age groups, including children and older adults, and diverse races, ethnicities, genders, and health backgrounds.
Digital Object Identifier (DOI)
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