GOurmet: A Tool for Comparing Gene Expression Profiles
Author Information
Author(s): Jason M. Doherty, Lynn K. Carmichael, Jason C. Mills
Primary Institution: Washington University School of Medicine
Hypothesis
Can software tools effectively compare and visualize gene expression profiles using gene ontology distributions?
Conclusion
GOurmet is a user-friendly software package that facilitates the analysis of multiple gene expression profiles.
Supporting Evidence
- GOurmet allows users to visualize and compare gene expression profiles based on GO term distributions.
- The software is designed to work independently of the platform used to generate the expression profiles.
- GOurmet includes a unique Targetoid plot for dynamic visualization of clustering data.
Takeaway
GOurmet helps scientists compare different gene expression data easily, like putting together a puzzle to see how different pieces fit together.
Methodology
GOurmet analyzes gene lists to compute GO term distributions and compares these profiles using clustering and visualization tools.
Limitations
The program does not provide assessments of error or statistical significance for profile clusters.
Digital Object Identifier (DOI)
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