Antimicrobial Activity of Medicinal Plants Against Oral Cancer Infections
Author Information
Author(s): Panghal Manju, Kaushal Vivek, Yadav Jaya P
Primary Institution: M. D. University, Rohtak, Haryana, India
Hypothesis
Can medicinal plants effectively control secondary infections in immunocompromised oral cancer patients?
Conclusion
The study concluded that certain medicinal plants can serve as effective antimicrobial agents against secondary infections in treated oral cancer patients.
Supporting Evidence
- 87.5% of the patients were observed as neutropenic.
- Eight medicinal plants showed significant antimicrobial activity against most of the isolates.
- The MIC and MFC values ranged from 31 to 500 μg/ml.
- P. aeruginosa was the most susceptible bacteria observed.
Takeaway
This study found that some plants can help fight infections in cancer patients whose immune systems are weak.
Methodology
Blood and oral swab cultures were taken from 40 oral cancer patients, and the antimicrobial activity of ten medicinal plants was evaluated using various microbiological methods.
Limitations
The study did not explore the toxic effects of the plant extracts on eukaryotic cells.
Participant Demographics
Patients undergoing treatment for oral cancer at a regional cancer institute.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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