Atypical manifestation of late onset limb girdle muscular dystrophy presenting with recurrent falling and shoulder dysfunction: a case report
2008

Atypical Late Onset Limb Girdle Muscular Dystrophy Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Schofer Markus Dietmar, Patzer Thilo, Quante Markus

Primary Institution: University Hospital Marburg, Germany

Hypothesis

Can late onset limb girdle muscular dystrophy present atypically in middle-aged patients?

Conclusion

This case highlights the importance of considering late onset muscular dystrophy in elderly patients with unexplained muscle atrophy and falls.

Supporting Evidence

  • The patient showed marked muscle atrophy and a rotator cuff tear.
  • Previous treatments for shoulder pain and dysfunction were ineffective.
  • Immunohistochemistry revealed a mild form of limb girdle muscular dystrophy.

Takeaway

A 54-year-old woman had muscle weakness and falls, which turned out to be a rare type of muscle disease that is often missed in older people.

Methodology

The case was diagnosed through clinical evaluation, MRI, serum creatine kinase measurement, and muscle biopsy.

Potential Biases

Potential bias in diagnosis due to atypical presentation and previous misattribution of symptoms.

Limitations

The study is based on a single case, limiting generalizability.

Participant Demographics

54-year-old Caucasian woman.

Digital Object Identifier (DOI)

10.1186/1757-1626-1-402

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