Comparing Contrast Media in Hysterosalpingography
Author Information
Author(s): Hazman Mohd. Nor, Jayapragasam KJ, Abdullah BJJ
Primary Institution: Department of Biomedical Imaging, University of Malaya
Hypothesis
To compare the diagnostic image quality between three different water soluble iodinated contrast media in hysterosalpingography (HSG).
Conclusion
Low osmolar contrast media (Iopramide and Ioxaglate) had diagnostic image quality comparable to the conventional high osmolar (Iodamide), but all three were too dense for detecting intrauterine pathology.
Supporting Evidence
- Visualisation of fimbrial rugae was significantly better with Iopramide and Ioxaglate than Iodamide.
- All contrast media provided acceptable diagnostic image quality for uterine and fallopian tube outlines.
- Higher incidence of contrast intravasation was noted in the Iodamide group.
Takeaway
This study looked at different types of liquids used in a special X-ray to see inside the uterus and found that some worked better than others, but all were too thick to see some problems inside.
Methodology
A prospective, randomised, double-blind study comparing the diagnostic image quality of three types of water soluble iodinated contrast media in HSG on 204 patients.
Potential Biases
Differences in injection pressure and timing may have influenced the visualisation of anatomical structures.
Limitations
The HSG examination was not done by the same investigator, which may have affected consistency in results.
Participant Demographics
Patients included a mix of races with a mean age around 30 years.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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