Forty Years of the Use of Cells for Cartilage Regeneration: The Research Side
2024

Forty Years of the Use of Cells for Cartilage Regeneration

publication Evidence: moderate

Author Information

Author(s): Roseti Livia, Cavallo Carola, Desando Giovanna, D’Alessandro Martina, Grigolo Brunella

Primary Institution: Laboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

Conclusion

The review emphasizes the importance of understanding the role and mechanisms of different cell compounds to implement personalized treatments for cartilage regeneration.

Supporting Evidence

  • Implanted autologous cells have led to a new treatment option focused on regeneration.
  • Gene therapy is highlighted as a valuable tool for enhancing current regenerative treatments.
  • Different cell types, including mesenchymal stem cells, are explored for their potential in cartilage repair.

Takeaway

This study looks at how cells can help heal damaged cartilage and discusses new methods to make these treatments better.

Methodology

This is a review article summarizing biological and clinical advances in cartilage regeneration using various cell types and techniques.

Limitations

The review does not provide original experimental data and relies on existing literature, which may have varying quality.

Digital Object Identifier (DOI)

10.3390/pharmaceutics16121622

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