Structure of the Tree Shrew Cornea
Author Information
Author(s): Almubrad Turki, Akhtar Saeed
Primary Institution: King Saud University
Hypothesis
The study aims to describe the ultrastructure of corneal layers, collagen fibrils, and proteoglycans in the tree shrew cornea.
Conclusion
The structure of the tree shrew cornea is very similar to that of the normal human cornea.
Supporting Evidence
- The tree shrew cornea consists of 5 layers similar to the human cornea.
- The thickness of the tree shrew cornea is approximately half that of the human cornea.
- The minimum diameter of collagen fibrils in the tree shrew cornea is 39±4.25 nm.
Takeaway
The tree shrew's cornea has layers and structures similar to a human's, which makes it a good model for studying eye diseases.
Methodology
Corneas from tree shrews and humans were fixed, processed for electron microscopy, and analyzed for structural measurements.
Limitations
The study is limited to young tree shrew specimens, which may not represent the adult cornea.
Participant Demographics
Tree shrews aged 5, 6, and 10 weeks; human corneas from males aged 24, 25, and 54 years.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
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