Absolute standard hydrogen electrode potential and redox potentials of atoms and molecules: machine learning aided first principles calculations
2025

Predicting Redox Potentials with Machine Learning

publication Evidence: high

Author Information

Author(s): Jinnouchi Ryosuke, Karsai Ferenc, Kresse Georg

Primary Institution: Toyota Central R&D Labs., Inc.

Hypothesis

Can machine learning improve the accuracy of predicting the absolute standard hydrogen electrode potential and redox potentials of various molecules and atoms?

Conclusion

The study demonstrates that a hybrid functional with machine learning can accurately predict redox potentials with an average error of 140 mV.

Supporting Evidence

  • The hybrid functional can predict redox potentials across a wide range of potentials.
  • The method achieved an average error of 140 mV in predicting redox potentials.
  • Machine learning models were trained on semi-local exchange-correlation functionals.

Takeaway

This study shows how computers can help scientists predict important chemical properties, like how easily substances can gain or lose electrons, using smart algorithms.

Methodology

The study used machine learning models combined with first-principles calculations to predict redox potentials through thermodynamic integration.

Limitations

The computational cost remains high for accurate predictions, and the method may introduce errors from approximations.

Statistical Information

Confidence Interval

−4.52 ± 0.09 V for ASHEP

Digital Object Identifier (DOI)

10.1039/d4sc03378g

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