Late onset cerebellar ataxia syndrome after non-paraneoplastic Lambert-Eaton myasthenic syndrome: a case study
2025
Case of Late Onset Cerebellar Ataxia After Lambert-Eaton Myasthenic Syndrome
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Randall David P., Randall Matthew C.
Primary Institution: Advocate Health
Conclusion
This case highlights a rare instance of two neurological syndromes occurring in the same patient without an underlying cancer.
Supporting Evidence
- The patient had a history of Lambert-Eaton Myasthenic Syndrome five years before developing cerebellar ataxia.
- Both conditions were responsive to treatment, but required different therapies.
- No malignancy was detected during follow-up imaging over ten years.
Takeaway
A man had two different neurological problems years apart, and both were linked to the same antibody issue, but he didn't have cancer.
Methodology
The patient was diagnosed through clinical history, electromyography, and antibody testing.
Limitations
The study is based on a single case, limiting generalizability.
Participant Demographics
A 56-year-old right-handed man.
Digital Object Identifier (DOI)
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