Quantification of the prevalence of harms in healthcare related to drug treatment: reflections regarding the use of definitions developed for other settings to estimate the magnitude of the problem
2025

Understanding Drug-Related Harms in Healthcare

publication Evidence: moderate

Author Information

Author(s): Susanna M. Wallerstedt, Mikael Hoffmann

Primary Institution: University of Gothenburg

Hypothesis

How can we accurately quantify the prevalence of drug-related harms in healthcare using existing definitions?

Conclusion

The study suggests that current definitions for adverse drug reactions and drug-related problems may lead to overestimation of drug-related harms in healthcare.

Supporting Evidence

  • Definitions for adverse drug reactions and drug-related problems are broader than necessary for healthcare settings.
  • High prevalence figures from studies may lead to unreliable estimates of drug-related harms.
  • Misinterpretation of drug-related problems can affect healthcare decision-making.

Takeaway

This study looks at how we define problems caused by medications and suggests that we might be counting too many issues that aren't really harmful.

Potential Biases

There is a risk of overestimating drug-related harms due to the broad definitions applied.

Limitations

The definitions used for quantifying drug-related harms may not be suitable for healthcare settings, leading to potential misinterpretations.

Digital Object Identifier (DOI)

10.1007/s00228-024-03766-7

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