Serum selenium levels do not differ in type 2 diabetic subjects with and without coronary artery disease
2011

Selenium Levels in Diabetics with and without Heart Disease

Sample size: 200 publication Evidence: moderate

Author Information

Author(s): Sotiropoulos Alexios, Papadodima Stavroula A, Papazafiropoulou Athanasia K, Ioannidis Aggelos, Kokkinari Athanasia, Apostolou Ourania, Spiliopoulou Chara A, Athanaselis Sotirios

Primary Institution: General Hospital of Nikaia 'Ag. Panteleimon' - Piraeus, Greece

Hypothesis

Do selenium levels differ between type 2 diabetic subjects with and without coronary artery disease?

Conclusion

Serum selenium levels did not differ between diabetic subjects with and without CAD.

Supporting Evidence

  • Selenium levels were measured in 200 diabetic subjects.
  • No significant difference in selenium levels was found between the two groups.
  • Determinants of selenium levels included sex and glucose levels in those with CAD.

Takeaway

The study found that the amount of selenium in the blood is the same for people with diabetes whether or not they have heart disease.

Methodology

200 type 2 diabetic subjects were studied, with 100 having CAD and 100 not having CAD, and their selenium levels were measured.

Potential Biases

Potential biases due to the exclusion of subjects on selenium supplements and the specific population studied.

Limitations

No power sample calculation was performed, and the study was retrospective, limiting causal conclusions.

Participant Demographics

200 type 2 diabetic subjects, 100 with CAD and 100 without CAD, with a mix of genders.

Statistical Information

P-Value

0.16

Statistical Significance

p = 0.16

Digital Object Identifier (DOI)

10.1186/1756-0500-4-270

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