Colorectal Leakage After Surgery for Endometrial Cancer
Author Information
Author(s): Yamamura Akitoshi, Hamanishi Junzo, Yamanoi Koji, Sunada Masumi, Taki Mana, Mizuno Rin, Okada Yukiko, Murakami Ryusuke, Aisu Yuki, Maekawa Hisatsugu, Yamaguchi Ken, Mandai Masaki
Primary Institution: Kyoto University Graduate School of Medicine
Hypothesis
What are the safety and efficacy of conversion surgery after lenvatinib and pembrolizumab therapy for unresectable endometrial cancer?
Conclusion
Conversion surgery after lenvatinib and pembrolizumab therapy can lead to complications such as anastomotic leakage.
Supporting Evidence
- The patient had significant tumor shrinkage after treatment with lenvatinib and pembrolizumab.
- Postoperative complications included an anastomotic leakage requiring further surgery.
- The study highlights the need for caution in surgical decisions after antiangiogenic therapy.
Takeaway
A woman with advanced endometrial cancer had surgery after treatment, but she developed a leak in her bowel connection afterward.
Methodology
The patient underwent conversion surgery after treatment with lenvatinib and pembrolizumab, followed by monitoring for complications.
Limitations
This is a single case report, limiting the generalizability of the findings.
Participant Demographics
A 37-year-old woman with unresectable advanced endometrial cancer.
Digital Object Identifier (DOI)
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