Antimicrobial Activity of Lizard Decoctions
Author Information
Author(s): Israel J. M. Santos, Matias Edinardo F. F., Santos Karla K. A., Braga Maria F. B. M., Andrade Jacqueline C., Souza Teógenes M., Santos Francisco A. V., Sousa Ana Carla A., Costa José G. M., Menezes Irwin R. A., Alves Rômulo R. N., Almeida Waltecio O., Coutinho Henrique D. M.
Primary Institution: Regional University of Cariri-URCA
Hypothesis
Do the decoctions of Tropidurus hispidus and Tropidurus semitaeniatus have antimicrobial activity against bacterial strains?
Conclusion
The decoctions of T. hispidus and T. semitaeniatus did not show antimicrobial activity alone but enhanced the effectiveness of certain antibiotics.
Supporting Evidence
- The decoctions did not show a clinically relevant antibacterial activity.
- The minimal inhibitory concentration (MIC) was ≥1024 μg/mL against all bacterial strains tested.
- A synergistic effect was observed when decoctions were combined with aminoglycoside antibiotics.
Takeaway
The lizard teas didn't work on their own to fight germs, but they helped some medicines work better.
Methodology
The study involved preparing decoctions from the lizards and testing their antimicrobial activity against various bacterial strains, both alone and in combination with antibiotics.
Limitations
The decoctions did not demonstrate clinically relevant antibacterial activity, suggesting their ineffectiveness in treating bacterial infections.
Digital Object Identifier (DOI)
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