Adalimumab induced mononeuritis multiplex in a patient with refractory rheumatoid arthritis: a case report
2008
Adalimumab and Mononeuritis Multiplex in Rheumatoid Arthritis
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Makol Ashima, Grover Madhusudan
Primary Institution: Michigan State University
Hypothesis
Can adalimumab therapy lead to mononeuritis multiplex in patients with rheumatoid arthritis?
Conclusion
Stopping adalimumab therapy led to the complete resolution of neurological symptoms in the patient.
Supporting Evidence
- The patient developed mononeuritis multiplex four weeks after starting adalimumab therapy.
- Electromyography showed axonal neuropathy consistent with mononeuritis multiplex.
- Symptoms resolved after stopping adalimumab and starting corticosteroids.
Takeaway
A man with severe arthritis got a painful nerve problem after starting a new medicine, but he got better after stopping it.
Methodology
Case report detailing the patient's medical history, symptoms, and treatment response.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
54-year-old Caucasian male with a history of rheumatoid arthritis.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website