Comparative and Functional Genomics
2003

Microarray Analysis of Cardiac Fibrosis in Renal Failure

publication

Author Information

Author(s): Kerstin Amann, James Campanella, Ilya Shmulevich, Raymund Stefancsik, Ian Dunham, Jiri Forejt, Anne Cambon-Thomsen, Catherine Abbott, Vincent Schachter, Phillip Lord, Robert Stevens, Christian Blaschke

Conclusion

The study observed patterns of gene activation related to signaling pathways involved in cardiac remodelling during renal failure.

Supporting Evidence

  • The study used microarrays to analyze cardiac fibrosis in a rat model.
  • Gene activation patterns were linked to signaling pathways in cardiac remodelling.

Takeaway

Researchers looked at how genes behave in rats with heart problems caused by kidney failure.

Methodology

Microarray analysis was used to study gene activation patterns in a rat model.

Digital Object Identifier (DOI)

10.1002/cfg.344

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