Determinants of cardiovascular disease and other non-communicable diseases in Central and Eastern Europe: Rationale and design of the HAPIEE study
2006

HAPIEE Study: Understanding Cardiovascular Disease in Eastern Europe

Sample size: 36500 publication Evidence: high

Author Information

Author(s): Anne Peasey, Martin Bobak, Ruzena Kubinova, Sofia Malyutina, Andrzej Pajak, Abdonas Tamosiunas, Hynek Pikhart, Amanda Nicholson, Michael Marmot

Primary Institution: University College London

Hypothesis

The study investigates the role of alcohol, nutrition, and psychosocial factors as determinants of cardiovascular disease in Central and Eastern Europe.

Conclusion

The HAPIEE study aims to provide insights into the social, behavioral, and biological factors influencing cardiovascular risk and mortality in Eastern Europe.

Supporting Evidence

  • Socioeconomic factors are powerful determinants of mortality in Eastern Europe.
  • Alcohol consumption patterns have been linked to fluctuations in mortality rates.
  • Low fruit and vegetable intake is associated with increased cardiovascular disease risk.

Takeaway

This study looks at how things like what people eat, their drinking habits, and their social lives affect heart health in Eastern Europe.

Methodology

The study involves four cohorts from Russia, Poland, the Czech Republic, and Lithuania, with data collected through questionnaires and medical examinations.

Potential Biases

Participants may be healthier than non-respondents, which could skew results.

Limitations

Response rates may be affected by non-respondent bias, and the study's findings may not be generalizable beyond the cohorts studied.

Participant Demographics

Men and women aged 45-69 years, stratified by gender and age groups.

Digital Object Identifier (DOI)

10.1186/1471-2458-6-255

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