Recruitment and retention in a multicentre randomised controlled trial in Bell's palsy: A case study
2007

Recruitment and Retention in a Bell's Palsy Trial

Sample size: 551 publication Evidence: moderate

Author Information

Author(s): Brian McKinstry, Victoria Hammersley, Fergus Daly, Frank Sullivan

Primary Institution: Community Health Sciences, University of Edinburgh

Hypothesis

Can effective recruitment and retention strategies improve participation in a trial for Bell's palsy treatment?

Conclusion

Recruitment and retention in multi-centre trials from primary care can be successfully achieved with the right strategies.

Supporting Evidence

  • The trial successfully recruited 551 patients, exceeding the target of 550.
  • Retention rates were higher than expected, contributing to the overall success of the trial.
  • Recruitment strategies included home visits and financial incentives for participating practices.

Takeaway

This study shows that getting people to join and stay in a medical trial can be done well if you make it easy and important for doctors and patients.

Methodology

A 22 factorial randomized controlled trial involving patients with Bell's palsy, using home visits for recruitment and follow-up.

Potential Biases

Potential bias due to the exclusion of patients who were notified more than 72 hours after onset.

Limitations

The recruitment rate did not meet initial expectations, and there were variations in recruitment across study sites.

Participant Demographics

Patients with Bell's palsy, primarily aged 30-45 years.

Digital Object Identifier (DOI)

10.1186/1471-2288-7-15

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