Anti cancer effects of curcumin: cycle of life and death
2008

Anti-cancer effects of curcumin

publication Evidence: moderate

Author Information

Author(s): Sa Gaurisankar, Das Tanya

Primary Institution: Bose Institute

Hypothesis

Curcumin asserts its anti-tumor activity in cancer cells by altering the deregulated cell cycle via cyclin-dependent, p53-dependent, and p53-independent pathways.

Conclusion

Curcumin has significant potential as an anti-cancer agent by modulating cell cycle regulation and inducing apoptosis in cancer cells.

Supporting Evidence

  • Curcumin can suppress cancer cell proliferation and induce apoptosis.
  • It has been shown to inhibit angiogenesis and modulate cell cycle regulatory proteins.
  • Curcumin is safe for normal cells while effectively targeting cancer cells.

Takeaway

Curcumin, a spice from turmeric, can help fight cancer by stopping cancer cells from growing and making them die, while being safe for normal cells.

Methodology

The review discusses various studies on curcumin's effects on cell cycle regulation and its anti-cancer properties.

Limitations

The review is based on existing literature and may not include all recent studies or clinical trials.

Digital Object Identifier (DOI)

10.1186/1747-1028-3-14

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication