Intracranial Hypertension and Optic Neuritis in Two Unrelated Seronegative Cases
2024

Intracranial Hypertension and Optic Neuritis in Two Unrelated Children

Sample size: 2 publication Evidence: low

Author Information

Author(s): Reza Nejad Shahrokh Abadi, Farid Shekarchian, Farrokh Seilanian Toosi, Ahmadreza Mashreghi, Sara Maddahpour, Samane Kamali, Shima Shekari, Mehran Beiraghi Toosi, Narges Hashemi

Primary Institution: Mashhad University of Medical Sciences

Hypothesis

Can Intracranial Hypertension occur alongside Optic Neuritis in children without identifiable underlying causes?

Conclusion

The study presents two cases of children with concurrent Intracranial Hypertension and Optic Neuritis without any identifiable underlying conditions.

Supporting Evidence

  • Both patients presented with high cerebrospinal fluid opening pressures.
  • Optic Neuritis is not typically associated with Intracranial Hypertension.
  • Comprehensive diagnostic assessments were conducted to rule out other conditions.

Takeaway

This study shows that two kids had high pressure in their brain fluid and vision problems, but doctors couldn't find out why.

Methodology

The study involved clinical assessments, MRI scans, and laboratory tests to evaluate the conditions of the patients.

Limitations

The study is limited by the small sample size and the lack of identifiable underlying causes for the conditions.

Participant Demographics

Two adolescent girls, aged 15 and 13, both from non-consanguineous families.

Digital Object Identifier (DOI)

10.1002/ccr3.70041

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