Bioinformatic Resources for Exploring Human–virus Protein–protein Interactions Based on Binding Modes
2024

Bioinformatic Resources for Human-Virus Protein Interactions

publication Evidence: moderate

Author Information

Author(s): Huimin Chen, Jiaxin Liu, Gege Tang, Gefei Hao, Guangfu Yang

Primary Institution: Central China Normal University

Hypothesis

The review aims to provide a comprehensive summary of bioinformatic resources for exploring human-virus protein-protein interactions (PPIs).

Conclusion

The study highlights the need for improved bioinformatic tools to facilitate the exploration of human-virus PPIs and enhance antiviral drug development.

Supporting Evidence

  • Human-virus protein-protein interactions are crucial for understanding viral infections.
  • Existing databases often lack comprehensive data and drug-related information.
  • Machine learning techniques are increasingly used to predict human-virus interactions.

Takeaway

This study reviews tools that help scientists understand how human proteins interact with viruses, which is important for developing treatments.

Methodology

The review surveys and compares various bioinformatic resources and tools for human-virus PPIs.

Limitations

The review notes that many databases are not comprehensive and lack drug-related information.

Digital Object Identifier (DOI)

10.1093/gpbjnl/qzae075

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication