Antimicrobial Effect of Bitter Gourd Oil on Periodontal Pathogens
Author Information
Author(s): Muacevic Alexander, Adler John R, Jayaraj Pranavi, Ramakrishnan Hemalatha, Paulraj Surya, Govindarajan Priyadarshini, Muralidharan Haritha, Prabakar Manasa
Primary Institution: Karpaga Vinayaga Institute of Dental Sciences
Hypothesis
This study aims to assess the antimicrobial activity of bitter gourd oil against early colonizing microorganisms of chronic periodontitis.
Conclusion
Bitter gourd oil demonstrates antibacterial properties against Streptococcus pyogenes, making it a potential therapy for periodontal disease.
Supporting Evidence
- Phytochemical analysis identified alkaloids, terpenoids, flavonoids, and phenols in the oil sample.
- Higher concentrations of bitter gourd oil exhibited larger zones of inhibition against Streptococcus pyogenes.
- Amoxicillin demonstrated a substantially greater zone of inhibition compared to bitter gourd oil.
Takeaway
Bitter gourd oil can help fight bacteria that cause gum disease, and it might be a good alternative to traditional antibiotics.
Methodology
In vitro study using plaque samples from 10 subjects with chronic periodontitis to determine the minimum inhibitory concentration (MIC) of bitter gourd oil against Streptococcus pyogenes using the disc diffusion method.
Limitations
Limited sample size and evaluation of antimicrobial action on only primary colonizing pathogenic bacteria.
Participant Demographics
Subjects aged between 30 and 50 years, systemically healthy individuals with chronic periodontitis.
Statistical Information
P-Value
<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website