Not All Children with Under-Control Asthma are Controlled
2008

Asthma Control in Children

Sample size: 134 publication Evidence: moderate

Author Information

Author(s): Ricci G, Dondi A, Calamelli E, Dell’Omo V, Pagliara L, Belotti T, Masi M

Primary Institution: Department of Paediatrics, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

Hypothesis

Can spirometry and bronchodilation tests reveal subclinical airway abnormalities in children with asthma who appear to be under control?

Conclusion

Many children with asthma who seem to be under control actually have airway issues that can improve with therapy adjustments.

Supporting Evidence

  • 17.3% of children with controlled asthma had a positive bronchodilation test.
  • Patients with therapy adjustments showed improved lung function and quality of life.
  • The study highlights the importance of spirometry in assessing asthma control.

Takeaway

Some kids with asthma might look fine but actually have hidden problems in their lungs. Checking their lung function can help doctors give them better medicine.

Methodology

The study involved spirometry and bronchodilation tests on 134 children aged 6 to 17 with asthma to assess lung function and therapy effectiveness.

Potential Biases

Potential bias in symptom reporting from parents may lead to underestimation of asthma severity.

Limitations

The study did not include Exhaled Nitric Oxide measurements, which could provide additional information on inflammation.

Participant Demographics

134 children aged 6 to 17, with 98 males and a diagnosis of allergic asthma.

Statistical Information

P-Value

p≤0.001

Statistical Significance

p≤0.05

Digital Object Identifier (DOI)

10.2174/1874306400802010001

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