Impact of Left Ventricular Trabeculations and Papillary Muscles on Heart Measurements
Author Information
Author(s): Chuang Michael L, Gona Philimon, Hautvast Gilion LTF, Salton Carol J, Blease Susan J, Yeon Susan B, Breeuwer Marcel, O'Donnell Christopher J, Manning Warren J
Primary Institution: The NHLBI's Framingham Heart Study, Framingham, MA, USA
Hypothesis
How do left ventricular trabeculations and papillary muscles affect cavity volume and ejection fraction in cardiac imaging?
Conclusion
Left ventricular trabeculations and papillary muscles occupy 22% of the heart's blood pool, and adjusting for their volume increases the ejection fraction.
Supporting Evidence
- Men had greater heart volumes than women before adjustment.
- After adjustment, ejection fraction increased for both sexes.
- The adjustment method was highly reproducible.
Takeaway
The study found that parts of the heart called trabeculations and papillary muscles take up space in the heart's blood pool, and when we account for them, the heart works better.
Methodology
The study analyzed CMR images from 1494 adults using automated software to measure heart volumes and ejection fraction before and after adjusting for trabeculations and papillary muscles.
Participant Demographics
1494 adults, average age 64 years, 795 women.
Statistical Information
P-Value
p<0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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