Atherogenic Index of Plasma and Acute Coronary Syndrome Outcomes
Author Information
Author(s): S. Jiang, Liu Suying, Xiao Guie, Liu Kexuan, Li Jialin
Primary Institution: Shaoyang Central Hospital, Shaoyang, China
Hypothesis
Is there an association between the atherogenic index of plasma (AIP) and the risk of major cardiovascular adverse events (MACE) in patients with acute coronary syndrome (ACS)?
Conclusion
A high AIP is associated with an increased risk of MACE in patients with ACS, particularly for older patients.
Supporting Evidence
- A high AIP at admission was associated with an increased risk of MACE during follow-up.
- Older patients showed a stronger association between high AIP and increased MACE risk.
- Subgroup analyses indicated that the association was more pronounced in studies with a higher proportion of patients with diabetes.
Takeaway
If you have a high atherogenic index of plasma, you might be more likely to have serious heart problems, especially if you're older.
Methodology
A meta-analysis of nine cohort studies was conducted to evaluate the association between AIP and MACE in ACS patients.
Potential Biases
Potential selection and recall biases in retrospective studies.
Limitations
Five studies were retrospective, which may introduce biases; variability in AIP cutoff values among studies; reliance on observational data.
Participant Demographics
Adult patients with ACS, mean ages ranging from 57.4 to 61.3 years, with a male proportion of 66.9% to 81.9%.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 1.30–1.82
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website