Effect of Wild Strawberry Extract on Inflammatory Bowel Disease in Rats
Author Information
Author(s): Kanodia Lalit, Borgohain Mondita, Das Swranamoni
Primary Institution: Assam Medical College, Dibrugarh, India
Hypothesis
The study investigates the potential of Fragaria vesca extract to ameliorate experimentally induced inflammatory bowel disease (IBD) in rats.
Conclusion
The ethanolic extract of Fragaria vesca significantly improved symptoms of experimentally induced IBD in rats, likely due to its antioxidant and anti-inflammatory properties.
Supporting Evidence
- The extract significantly reduced colon weight and disease activity index compared to the control group.
- There was a notable decrease in macroscopic and microscopic lesion scores with the extract treatment.
- Biochemical assessments showed improved levels of myeloperoxidase, catalase, and superoxide dismutase.
Takeaway
Researchers tested a fruit extract from wild strawberries on sick rats and found it helped them feel better by reducing inflammation.
Methodology
Albino rats were divided into four groups and treated with different substances, including the strawberry extract, before inducing colitis with acetic acid and assessing the effects.
Limitations
The study was conducted on rats, and results may not directly translate to humans.
Participant Demographics
Healthy Wistar albino rats weighing 150-200 g.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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