1-(2-Chlorophenyl)-6-fluoro-2-methyl-1H-indole-3-carbonitrile
2011
Crystal Structure of a New Indole Compound
publication
Evidence: moderate
Author Information
Author(s): Yang Kun, Li Pei-Fan, Liu Yan, Fang Zhi-Zhong
Primary Institution: Tianjin Medical University
Conclusion
The study successfully determined the crystal structure of the indole derivative, revealing important geometric and interaction details.
Supporting Evidence
- The dihedral angle between the indole ring system and the benzyl ring is 80.91°.
- The crystal packing features various interactions including C—H⋯Cl and C—H⋯F.
- The study contributes to understanding the structure-activity relationship of indoles.
Takeaway
The researchers looked at a new chemical compound and figured out how its atoms are arranged, which is important for understanding how it might work in medicine.
Methodology
The compound was synthesized and its crystal structure was analyzed using X-ray diffraction.
Digital Object Identifier (DOI)
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