C. trachomatis in Female Reproductive Tract Infections and RFLP-Based Genotyping: A 16-Year Study from a Tertiary Care Hospital
2011

Chlamydia trachomatis Infections in Women: A 16-Year Study

Sample size: 2466 publication Evidence: moderate

Author Information

Author(s): Gita Satpathy, Suneeta Mittal, Anjana Sharma, Niranjan Nayak, Sujata Mohanty, Pandey R. M.

Primary Institution: All India Institute of Medical Sciences, New Delhi, India

Hypothesis

What is the prevalence of Chlamydia trachomatis in female reproductive tract infections over a 16-year period?

Conclusion

Chlamydia antigen was detected in 15.85% of women studied, with significant rates in those with pelvic inflammatory disease and cervicitis.

Supporting Evidence

  • Chlamydia antigen was detected in 391 out of 2466 women studied.
  • 15.85% of patients tested positive for Chlamydia.
  • 27.27% of women with pelvic inflammatory disease tested positive.
  • 16.74% of women with cervicitis tested positive.
  • 16.03% of women with infertility tested positive.
  • 12.06% of women with adverse pregnancy outcomes tested positive.

Takeaway

The study found that many women have a germ called Chlamydia that can cause health problems, and it was found in about 16 out of every 100 women tested.

Methodology

The study used direct immunofluorescence assay, tissue culture isolation, and PCR assay to detect Chlamydia in cervical specimens.

Potential Biases

Potential selection bias as the sample was taken from women attending a tertiary care hospital.

Limitations

The study only included women attending a specific hospital, which may not represent the general population.

Participant Demographics

Women aged 20-50 years attending the Obstetrics and Gynecology Clinic.

Statistical Information

P-Value

0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/548219

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