Clamp-Crushing versus stapler hepatectomy for transection of the parenchyma in elective hepatic resection (CRUNSH) - A randomized controlled trial (NCT01049607)
2011

Comparing Clamp-Crushing and Stapler Techniques in Liver Surgery

Sample size: 130 publication Evidence: moderate

Author Information

Author(s): Rahbari Nuh N, Elbers Heike, Koch Moritz, Bruckner Thomas, Vogler Patrick, Striebel Fabian, Schemmer Peter, Mehrabi Arianeb, Büchler Markus W, Weitz Jürgen

Primary Institution: University of Heidelberg, Germany

Hypothesis

Does stapler hepatectomy reduce intraoperative blood loss compared to the clamp-crushing technique during elective hepatic resection?

Conclusion

The study aims to determine if stapler hepatectomy is more effective in reducing intraoperative blood loss than the clamp-crushing technique.

Supporting Evidence

  • The study is the first randomized controlled trial comparing stapler hepatectomy to clamp-crushing technique.
  • Intraoperative blood loss is a known predictor of postoperative complications.
  • The trial aims to provide high-level evidence on the effectiveness of stapler hepatectomy.

Takeaway

This study is trying to find out if using a stapler to cut the liver during surgery is better than the old method of crushing it, especially in terms of blood loss.

Methodology

This is a randomized controlled trial comparing two techniques for liver surgery, with patients assigned to either the clamp-crushing or stapler technique.

Potential Biases

Potential bias in blinding as the surgeon cannot be blinded to the technique used.

Limitations

The study is limited to a single center and may not be generalizable to other settings.

Participant Demographics

Patients scheduled for elective hepatic resection, aged 18 and older.

Digital Object Identifier (DOI)

10.1186/1471-2482-11-22

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