Using T1 Mapping to Diagnose Acute Pericarditis
Author Information
Author(s): Cau Riccardo, Pisu Francesco, Montisci Roberta, D’Angelo Tommaso, Mantini Cesare, Salgado Rodrigo, Saba Luca
Primary Institution: Azienda Ospedaliero Universitaria di Cagliari
Hypothesis
Can pericardial T1 mapping serve as a supportive non-contrast CMR parameter in diagnosing acute pericarditis?
Conclusion
Pericardial T1 mapping values could help identify patients with acute pericarditis and are associated with the severity of pericardial late gadolinium enhancement.
Supporting Evidence
- Acute pericarditis patients showed significantly lower pericardial T1 mapping values compared to controls.
- The diagnostic performance of pericardial T1 mapping was excellent, with an area under the curve of 0.97.
- Pericardial T1 mapping values were independently associated with the severity of pericardial late gadolinium enhancement.
Takeaway
Doctors can use a special imaging technique called T1 mapping to help find out if someone has a heart condition called acute pericarditis without needing to use contrast dye.
Methodology
This retrospective study analyzed CMR scans of 35 patients with acute pericarditis and 17 healthy controls, comparing pericardial T1 mapping values.
Potential Biases
The control group consisted of patients who underwent CMR for different reasons, which may introduce variability.
Limitations
The study had a small sample size and was retrospective, which may limit the generalizability of the findings.
Participant Demographics
35 patients with acute pericarditis (26 males, mean age 45.54 years) and 17 healthy controls (12 males, mean age 47.78 years).
Statistical Information
P-Value
0.001
Confidence Interval
95% CI = 0.94–0.98
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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