Spinal Cord Compression as the First Presentation of Primary Hyperoxaluria in a Patient With Kidney Failure: A Case Report and Literature Review
2024

Spinal Cord Compression from Primary Hyperoxaluria in Kidney Failure

Sample size: 1 publication 10 minutes Evidence: moderate

Author Information

Author(s): Kliea Marwa, Alsultan Mohammad, Qatleesh Safaa, Haroun Yousef, Aziz Osama Abdul, Basha Kassem

Primary Institution: Damascus University-Faculty of Medicine, Damascus, Syria

Hypothesis

Can primary hyperoxaluria present as spinal cord compression in patients with kidney failure?

Conclusion

The case highlights that primary hyperoxaluria can lead to severe complications like spinal cord compression due to calcium oxalate deposits.

Supporting Evidence

  • The patient presented with back pain and inability to walk due to spinal cord compression.
  • Biopsies confirmed calcium oxalate deposits in the vertebrae.
  • Only three similar cases of primary hyperoxaluria with spinal cord compression were found in the literature.

Takeaway

A woman with kidney failure had back pain and couldn't walk because of a rare condition that caused her spine to be compressed by calcium deposits.

Methodology

The case involved clinical examination, MRI imaging, and biopsies to diagnose primary hyperoxaluria and its effects.

Limitations

The patient did not undergo genetic testing due to cost, which limited the definitive diagnosis.

Participant Demographics

A 50-year-old woman with a history of kidney failure and other health issues.

Digital Object Identifier (DOI)

10.1016/j.xkme.2024.100932

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