Single-Lung Transplantation After Aborted Bilateral Lung Transplantation
Author Information
Author(s): Varun Puri, Tracey Guthrie, Masina Scavuzzo, Daniel Kreisel, Alexander S. Krupnick, G. Alexander Patterson, Bryan F. Meyers
Primary Institution: Washington University School of Medicine
Hypothesis
What are the outcomes of patients undergoing single-lung transplantation in the setting of aborted bilateral lung transplantation?
Conclusion
Patients undergoing single-lung transplantation in the setting of an aborted bilateral lung transplant may be at a higher risk of worse outcomes.
Supporting Evidence
- Of the 543 lung transplants performed, 31 were single-lung transplants.
- The one and two-year survival was 84% and 79% in the planned group and 62% and 52% in the aborted group.
- The aborted group had higher cardiopulmonary bypass utilization compared to the planned group.
Takeaway
This study looked at patients who had one lung transplanted after their doctors decided not to do a double lung transplant. It found that these patients might not do as well as those who had their single lung transplant planned from the start.
Methodology
A retrospective review of single lung transplants at an institutional program from January 2000 to December 2009.
Potential Biases
Potential biases may arise from the retrospective nature of the study and the reliance on institutional data.
Limitations
The small number of patients available for analysis may limit the statistical power of the findings.
Participant Demographics
The study included adult patients who underwent single-lung transplantation, with similar demographics in both planned and aborted groups.
Statistical Information
P-Value
0.02
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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