Organic Papers
2011
Study of a New Spiro Compound
publication
Evidence: moderate
Author Information
Author(s): Chen Jin-Xiang, Wang Yu-Qin, Liu Shu-Wen, Lin Wei-Er, Chen Zhi-Peng
Primary Institution: School of Pharmaceutical Science, Southern Medical University, Guangzhou, People’s Republic of China
Hypothesis
The title compound was synthesized through a new ring-rearrangement reaction.
Conclusion
The synthesized compound exhibits a unique crystal structure with specific hydrogen bonding interactions.
Supporting Evidence
- The compound was synthesized in one step through a new ring-rearrangement reaction.
- The indene ring is disordered over two sites with an occupancy ratio.
- Hydrogen bonding interactions contribute to the stability of the crystal structure.
Takeaway
Scientists made a new chemical compound that has a special structure, which could be important for medicine.
Methodology
The compound was synthesized using a reaction involving CuCl2 and ethanolamine, followed by extraction and recrystallization.
Digital Object Identifier (DOI)
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