Comparing Incremental Peritoneal Dialysis and Hemodialysis for Kidney Transplant
Author Information
Author(s): Domenici Alessandro, Comunian Maria Cristina, Fazzari Loredana, Sivo Francesca, Dinnella Angela, Della Grotta Barbara, Punzo Giorgio, Menè Paolo
Primary Institution: Sant'Andrea Hospital, Sapienza University of Rome
Hypothesis
Is incremental peritoneal dialysis a better option than hemodialysis as a bridge to kidney transplantation?
Conclusion
Incremental peritoneal dialysis leads to better outcomes in kidney transplant patients compared to hemodialysis.
Supporting Evidence
- Patients on incremental PD had lower epoetin requirements and better preservation of residual renal function.
- Delayed graft function occurred in only 1 patient on PD compared to 11 on HD.
- Serum creatinine levels were significantly higher in patients who had been on HD at discharge and one year later.
Takeaway
This study shows that patients who use a gentle form of kidney treatment called incremental peritoneal dialysis do better when they get a new kidney than those who use a different method called hemodialysis.
Methodology
This observational cohort study included stage 5 CKD patients who started either incremental peritoneal dialysis or hemodialysis and later received their first renal transplant.
Potential Biases
There may be a risk of bias due to unmeasured factors affecting transplant outcomes.
Limitations
The study had a small sample size and lacked control over certain donor and graft-related factors.
Participant Demographics
The study included 17 patients on incremental PD and 24 on HD, with a slightly higher prevalence of females in the PD group.
Statistical Information
P-Value
p<0.001
Confidence Interval
0.22 to 0.87
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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