Higher Cerebral Oxygen Saturation and Urinary Output in Pediatric Surgery
Author Information
Author(s): Miyamoto Takashi, Miyaji Kagami, Okamoto Hirotsugu, Kohira Satoshi, Tomoyasu Takahiro, Inoue Nobuyuki, Ohara Kuniyoshi
Primary Institution: Kitasato University School of Medicine
Hypothesis
Higher cerebral oxygen saturation during regional cerebral perfusion is correlated with urinary output.
Conclusion
Higher cerebral oxygenation may provide higher urinary output due to higher renal blood flow through collateral circulation.
Supporting Evidence
- Patients with higher cerebral oxygen saturation had significantly higher urinary output.
- A higher dose of Chlorpromazine was used in patients with higher cerebral oxygen saturation.
- The study included a diverse group of patients undergoing aortic arch repair.
Takeaway
If the brain gets more oxygen during surgery, the kidneys can work better and make more urine.
Methodology
The study analyzed urinary output and cerebral oxygen saturation in 12 patients who underwent aortic arch repair with regional cerebral perfusion.
Potential Biases
Potential biases due to the observational nature of the study.
Limitations
The study was retrospective and had a small sample size.
Participant Demographics
Patients aged 3 to 61 days, weighing 2.6 to 3.4 kg.
Statistical Information
P-Value
0.03
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website