My continuing adventure with 21 CFR Part 11--the evolution of Zymark's compliance
2001

Zymark's Journey to Compliance with 21 CFR Part 11

publication Evidence: moderate

Author Information

Author(s): Stephen M. Dobro

Primary Institution: Zymark Corporation

Hypothesis

How can Zymark ensure its laboratory automation equipment complies with 21 CFR Part 11?

Conclusion

Zymark successfully validated its products for compliance with 21 CFR Part 11, improving both product quality and customer satisfaction.

Supporting Evidence

  • Zymark developed a standard validation plan to evaluate both existing and new products.
  • The validation process included expert and customer reviews to ensure thoroughness.
  • Testing revealed non-compliance issues that were addressed with software updates.
  • The PreludeTM product was designed to be compliant from the start, demonstrating the effectiveness of the validation plan.

Takeaway

Zymark worked hard to make sure its lab equipment followed important rules about electronic records and signatures, which helps customers meet their needs.

Methodology

The study involved a chronological review of the validation process for Zymark's products to ensure compliance with 21 CFR Part 11.

Digital Object Identifier (DOI)

10.1080/14639240110092558

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication