Risk assessment does not explain high prevalence of gestational diabetes mellitus in a large group of Sardinian women
2008

High Prevalence of Gestational Diabetes in Sardinian Women

Sample size: 1103 publication 10 minutes Evidence: moderate

Author Information

Author(s): Cinzia Murgia, Rachele Berria, Luigi Minerba, Simonetta Sulis, Michela Murenu, Elaine Portoghese, Nicoletta Garau, Pierina Zedda, Gian Benedetto Melis

Primary Institution: Università degli Studi di Cagliari, Italy

Hypothesis

What factors contribute to the high prevalence of gestational diabetes mellitus (GDM) in Sardinian women?

Conclusion

The high prevalence of GDM in Sardinian women does not seem to be linked to the presence of known risk factors.

Supporting Evidence

  • The prevalence of GDM in the study population was 22.3%.
  • Obesity, prior GDM, and family history of Type 2 diabetes were significant risk factors.
  • Only patients over 35 years of age were more represented in the GDM group.

Takeaway

This study looked at why so many pregnant women in Sardinia have diabetes. It found that the usual reasons for diabetes didn't explain it.

Methodology

The study evaluated risk factors in 1103 pregnancies using logistic regression and assessed the association of these factors with GDM.

Potential Biases

Potential bias in self-reported family history of diabetes and prior obstetrical outcomes.

Limitations

The study did not compare its findings with other Italian regions using the same screening methods.

Participant Demographics

All participants were white and of Sardinian descent.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI 2.08–6.8

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1477-7827-6-26

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