3-(4-Chloro­phen­yl)-1-[(2R,4aR,8aR)-4a,8-dimethyl-1,2,3,4,4a,5,6,8a-octa­hydro­naphthalen-2-yl]prop-2-en-1-one
2011

Synthesis and Structure of a New Compound from Inula Viscosa

publication Evidence: moderate

Author Information

Author(s): Tebbaa Mohamed, Benharref Ahmed, Berraho Moha, Avignant Daniel, Oudahmane Abdelghani, Akssira Mohamed

Primary Institution: Université Hassan II, Mohammedia-Casablanca

Hypothesis

The study investigates the reactivity of isocostic acid derived from Inula Viscosa to synthesize new compounds.

Conclusion

The new compound was successfully synthesized with a yield of 90% and its structure was confirmed by NMR and X-ray analysis.

Supporting Evidence

  • The compound was synthesized with a yield of 90%.
  • The structure was confirmed by NMR and single-crystal X-ray analysis.
  • The cyclohexane ring adopts a chair conformation.

Takeaway

Scientists made a new chemical from a plant and found it was really good at making something useful.

Methodology

The compound was synthesized through a reaction involving isocostic acid and p-chlorobenzaldehyde, followed by purification and crystallization.

Digital Object Identifier (DOI)

10.1107/S1600536811016886

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