Genetic Study of Porcine Circovirus in Thai Piglets
Author Information
Author(s): Jantafong Tippawan, Boonsoongnern Alongkot, Poolperm Pariwat, Urairong Kitcha, Lekcharoensuk Chalermpol, Lekcharoensuk Porntippa
Primary Institution: Kasetsart University, Thailand
Hypothesis
This study aims to determine the association between occurrence of PMWS and PCV2 subtypes as well as genetically characterize PCV2 in Thailand.
Conclusion
The study found that PCV2 DNA was detected more frequently in PMWS-affected farms, indicating a correlation between PCV2 infection and PMWS occurrence.
Supporting Evidence
- PCV2 DNA was detected in 52 of 140 pigs (37.14%) from both farm categories.
- PCV2 was found in 50% of faecal swabs from PMWS-affected farms compared to 7.14% from PMWS-negative farms.
- The study identified a new subtype of PCV2 called PCV2e in addition to previously known subtypes.
Takeaway
The study looked at sick piglets in Thailand to see if a virus called PCV2 was making them sick, and found that the virus was more common in farms where the pigs were sick.
Methodology
PCV2 DNA was isolated from faecal swabs and whole blood of piglets from PMWS-affected and -negative farms, followed by PCR amplification and sequencing.
Limitations
The correlation between subtypes and virulence of PCV2 infection is not conclusive due to limited number of sequences from PMWS negative farms.
Participant Demographics
Piglets aged 5-10 weeks from both PMWS-affected and PMWS-negative farms.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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