Toxicological Evaluation of Pooled Selected Fractions of Mimosa invisa and Protective Effect of Herbal Decoction
2011

Toxicity Evaluation of Mimosa invisa and Herbal Decoction's Protective Effect

Sample size: 18 publication Evidence: moderate

Author Information

Author(s): Usha P.T.A., Gopakumar N., Chandrasekhran Nair A., N. Divakran

Primary Institution: College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, India

Hypothesis

Can a herbal decoction protect against the toxicity of Mimosa invisa in rabbits?

Conclusion

The study found that Mimosa invisa can cause kidney and liver toxicity in rabbits, but a herbal decoction can help protect these organs.

Supporting Evidence

  • Group II rabbits showed significant increases in liver and kidney toxicity markers after consuming Mimosa invisa.
  • Histopathological examination confirmed liver and kidney damage in the group that received the toxic fraction.
  • The herbal decoction reversed the biochemical and histopathological changes in the treated group.

Takeaway

This study shows that a plant called Mimosa invisa can make rabbits sick, but a special herbal tea can help them feel better.

Methodology

Eighteen adult rabbits were divided into three groups to test the toxicity of Mimosa invisa and the protective effect of a herbal decoction over 20 days.

Limitations

The study was limited to a small sample size of rabbits and may not be generalizable to other species.

Participant Demographics

Eighteen adult rabbits from a breeding station in Kerala, India.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.4103/0971-6580.75873

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