Ecologic Factors Associated with West Nile Virus Transmission, Northeastern United States
2008

Ecological Factors Linked to West Nile Virus Spread

Sample size: 977 publication Evidence: high

Author Information

Author(s): Heidi E. Brown, James E. Childs, Maria A. Diuk-Wasser, Durland Fish

Primary Institution: Yale University

Hypothesis

Human WNV disease is linked to the urban environment independent of human population density.

Conclusion

The study found that urbanization significantly increases the risk of West Nile virus disease incidence.

Supporting Evidence

  • Counties with less than 38% forest cover had 4.4 times greater odds of high WNV incidence.
  • Urbanization was identified as a significant risk factor for WNV disease incidence.
  • Data was collected from 1999 to 2006, covering 204 counties in 8 states.

Takeaway

This study shows that living in areas with less forest and more urban development makes people more likely to get sick from West Nile virus.

Methodology

The study analyzed 8 years of county-based human WNV disease surveillance data across 8 northeastern states.

Potential Biases

Potential biases in WNV incidence reporting due to unequal resource bases among counties.

Limitations

The spatial resolution of human surveillance data did not allow for finer evaluation of within-urban associations.

Participant Demographics

The study included data from 56.6 million residents in 8 northeastern states.

Statistical Information

P-Value

0.01

Confidence Interval

95% CI 1.4–13.2

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.3201/eid1410.071396

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