The ischemic area-at-risk on T2-weighted MRI shows recovery of systolic strain at 1 year
2011

Recovery of Heart Function After Heart Attack

Sample size: 16 publication Evidence: moderate

Author Information

Author(s): O'Regan Declan P, Ariff Ben, Neuwirth Clare, Tan Yvonne, Durighel Giuliana, Cook Stuart A

Primary Institution: Imperial College, London, UK

Hypothesis

Is there long-term improvement of regional strain in acutely ischemic myocardium following primary coronary intervention using cardiac magnetic resonance imaging?

Conclusion

The study found a long-term improvement in heart function in patients who had a heart attack and received treatment.

Supporting Evidence

  • All patients showed acute myocardial edema within the reperfused territory.
  • Mean myocardial salvage was 62±21% at baseline.
  • The mean infarct area decreased from 20±10.2% at baseline to 14±5.7% at 1 year follow-up.
  • Peak systolic midwall circumferential strain improved from -14.4±5.3% to -19.2±5.4%.

Takeaway

Doctors looked at how well the heart works after a heart attack and found that it gets better over time with the right treatment.

Methodology

The study involved 16 patients who had a heart attack and underwent cardiac MRI at baseline and one year after treatment.

Participant Demographics

Patients with acute ST elevation myocardial infarction who received primary coronary intervention.

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1532-429X-13-S1-P90

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