Anxiolytic Effects of Nymphaea alba in Mice
Author Information
Author(s): Thippeswamy B.S., Mishra Brijesh, Veerapur V.P., Gupta Gourav
Primary Institution: Sree Siddaganga College of Pharmacy, Tumkur, Karnataka, India
Hypothesis
The study aims to evaluate the anxiolytic effect of an ethanolic extract of Nymphaea alba Linn. in mice.
Conclusion
The study suggests that an ethanolic extract of N. alba may possess anxiolytic activity and supports its traditional use.
Supporting Evidence
- The extract significantly increased the time spent in open arms in the elevated plus maze test.
- In the light and dark test, the extract increased time spent in the light box and reduced immobility.
- The extract reduced aggressive behavior in the foot shock induced aggression test.
Takeaway
Researchers tested a plant called Nymphaea alba on mice to see if it helps reduce anxiety, and it seems to work well.
Methodology
The study used various tests including the elevated plus maze, light and dark test, and open field test to assess anxiety levels in mice treated with N. alba extract.
Participant Demographics
Male Swiss albino mice, 22–25 g.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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