Genomes of Taylorella equigenitalis from the Czech Republic isolated between 1982–2021
Author Information
Author(s): Hrala Matěj, Andrla Petr, Bosák Juraj, Fedrová Pavla, Mugutdinov Amir, Karpíšková Renata, Nedbalcová Kateřina, Raichová Jitka, Faldyna Martin, Hořín Petr, Šmajs David
Primary Institution: Masaryk University, Brno, Czech Republic
Hypothesis
The study aims to isolate contemporary strains of Taylorella equigenitalis, determine their genome sequences, evaluate their antibiotic resistance, and compare them with other strains.
Conclusion
The study revealed a recently emerged streptomycin resistance in Taylorella equigenitalis strains from Kladruber horses, emphasizing the need for antibiotic surveillance and alternative treatments.
Supporting Evidence
- Taylorella equigenitalis is the causative agent of sexually transmitted contagious equine metritis.
- Contemporary strains were found to be resistant to streptomycin, suggesting the recent emergence of this mutation.
- The study determined nine complete whole genome sequences of T. equigenitalis strains.
Takeaway
Scientists studied horse bacteria to see how they changed over time and found that some of them became resistant to a common antibiotic.
Methodology
The study used whole-genome sequencing and antibiotic susceptibility testing on samples collected from Kladruber stallions.
Potential Biases
The absence of a randomized or systematic sampling approach could result in sampling bias potentially affecting the observed genetic diversity.
Limitations
The study had a limited number of genomes examined from Czech samples (n = 9) and a relatively short sampling period (42 years).
Participant Demographics
All samples were collected from Kladruber stallions in the Czech Republic.
Statistical Information
Confidence Interval
95% HPD: 4.8564×10−7–8.6941×10−7
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website