Genomic assessment of novel antibacterial targets
2004
Genomic Assessment of Novel Antibacterial Targets
publication
Evidence: moderate
Author Information
Author(s): Tom White, Douglas Kell
Hypothesis
Can computational methods identify novel targets for antibacterial drugs?
Conclusion
The study successfully identified bacterial genes that could serve as potential drug targets.
Supporting Evidence
- The study used sequence conservation across pathogenic bacteria as a criterion.
- The absence of a human homologue was also considered in scoring bacterial genes.
Takeaway
Researchers used computers to find new ways to fight bacteria by looking for special genes that could be targeted by drugs.
Methodology
A computational approach was used to score and rank bacterial genes based on specific criteria.
Digital Object Identifier (DOI)
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