An infant with asymptomatic hepatic granuloma probably caused by bacillus Calmette-Guérin (BCG) vaccination found incidentally at autopsy: a case report
2008
Infant with Liver Granuloma After BCG Vaccination
publication
Evidence: low
Author Information
Author(s): Tajima Yutaka, Takagi Rie, Nakajima Tamiko, Kominato Yoshihiko
Primary Institution: Gunma University
Hypothesis
Is the hepatic granuloma in the infant related to BCG vaccination?
Conclusion
The asymptomatic granuloma in the infant was likely caused by BCG vaccination.
Supporting Evidence
- The infant was found dead with no prior symptoms.
- Granulomas were found in the liver but not in other organs.
- The infant had been vaccinated with BCG two months prior to death.
Takeaway
A baby had a lump in his liver after getting a vaccine, but he didn't show any symptoms. Doctors think the vaccine might have caused it.
Methodology
The infant underwent a complete autopsy, and various staining and PCR techniques were used to analyze tissue samples.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
5-month-old male infant.
Digital Object Identifier (DOI)
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