Allergic Sensitivity and Its Impact on Asthma and Rhinitis Severity in Chinese Patients
Author Information
Author(s): Li Jing, Huang Ying, Lin Xiaoping, Zhao Deyu, Tan Guolin, Wu Jinzhun, Zhao Changqing, Zhao Jing, Spangfort Michael D, Zhong Nanshan
Primary Institution: China Alliance of Research on Respiratory Allergic Disease (CARRAD)
Hypothesis
This study investigates the association between severity of asthma and rhinitis and degree of specific allergic sensitization in allergic patients in China.
Conclusion
Sensitization to certain allergens is associated with increased severity of rhinitis and asthma in Chinese patients.
Supporting Evidence
- Patients with moderate-severe intermittent rhinitis were more sensitized to outdoor allergens.
- Moderate-severe asthma was associated with sensitization to indoor allergens.
- Multiple allergen sensitization increased the severity of rhinitis and asthma.
Takeaway
If you are allergic to more things, you might have worse asthma and rhinitis symptoms.
Methodology
A cross-sectional survey was performed with 6304 patients who completed questionnaires and underwent skin prick tests.
Limitations
The study did not analyze data by stratification of patients by regions and seasons.
Participant Demographics
Patients aged 5 to 65 years with asthma and/or rhinitis from 17 cities in China.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI 1.07-1.14
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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