Molecular Epidemiology of Swine Flu in Gwalior, India
Author Information
Author(s): Shashi Sharma, Manmohan Parida, Jyoti Shukla, PVL Rao
Primary Institution: Defence Research & Development Establishment (DRDE), Gwalior, India
Hypothesis
What is the genetic makeup of the swine origin influenza virus circulating in Gwalior, India?
Conclusion
The study found that the swine flu virus in Gwalior showed 99% homology with other circulating strains and revealed the presence of two genetically distinct lineages.
Supporting Evidence
- The study confirmed the swine flu outbreak through specific gene assays.
- Full HA gene sequencing revealed high homology with other strains.
- Phylogenetic analysis showed circulation of two distinct lineages.
Takeaway
Scientists studied swine flu samples from people in Gwalior, India, and found that the virus was very similar to other strains found in the world.
Methodology
The study involved collecting nasopharyngeal swab samples and using RT-PCR and RT-LAMP assays for virus detection and sequencing.
Participant Demographics
Patients admitted to a military hospital in Gwalior, India.
Digital Object Identifier (DOI)
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