Effects of Fasting on Peptic Ulcer Disease During Ramadan
Author Information
Author(s): G. M. MALIK, M. MUBARIK, G. JEELANI, H. TAJAMUL, S. A. KADLA, B. A. LONE, M. D. KHAN
Primary Institution: S.M.H.S. Hospital Srinagar, Affiliated to Government Medical College Srinagar, Kashmir, India
Hypothesis
What are the effects of Ramadan fasting on patients with peptic ulcer disease?
Conclusion
Ramadan fasting may be hazardous for patients with peptic ulcer disease, especially those with active chronic ulcers.
Supporting Evidence
- Four patients with active acute duodenal ulcers showed signs of healing after Ramadan.
- Seven out of eight patients with active chronic duodenal ulcers bled during Ramadan.
- Two patients with erosive duodenitis showed complete healing after Ramadan.
Takeaway
This study looked at how fasting during Ramadan affects people with stomach ulcers. It found that fasting can make some ulcers worse.
Methodology
The study involved 23 fasting patients with peptic ulcer disease who underwent endoscopy before and after Ramadan, compared with 15 nonfasting control subjects.
Potential Biases
The results may be affected by variations in drug compliance among patients.
Limitations
The study had a small sample size and included 5 drug defaulters who developed gastrointestinal bleeding.
Participant Demographics
Of the 23 fasting patients, 20 (87%) were men and 3 (13%) were women, aged 21 to 65 years.
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